Ayesha was born and raised in Bannu but later on moved to Peshawar. She holds a degree of Bachelors in International Relations, BS in Computer Science, and Masters in Comparative Religions. Currently she is member of National Assembly representing Pakistan Tehreek-e-Insaf (PTI) on a reserved seat for women. Prior to joining PTI she has served as the Chief Coordinator of the Pakistan Peoples Party for FATA, and was also briefly part of All Pakistan Muslim League. She remains a vocal critic of US drone strikes in Pakistan.